Thursday, June 11, 2015

Skin Microbiota and Immunity- A Dialogue

I read with great interest this article titled Dialogue Between Skin Microbiota and Immunity, in Science.

The authors explore the interactions of microbes and immune cells on the skin surface with respect to disease and homeostatic states.  

For altered skin microbiota, especially when inflammatory or infectious complications ensue, there is a call for topical microbiotic therapy in the form of microbial creams that restore the balance skin's flora. 

I have previously written about chlorhexidine bathing for the prevention of hospital acquired infection. I cannot help but wonder what downstream effects may occur as we alter the cutaneous microbiome with chlorhexidine for the short term gain of preventing hospital acquired infections.

The human body has a normal microbial ecology. We alter it at our own risk.