Friday, October 2, 2015

Sepsis Video: Get Your Sepsy on!

We need not confine ourselves to boring, tedious, online slides sets and modules for our ongoing medical education.

See the video below from Kern Medical Center. Raising sepsis awareness, hammering home critical concepts and management points.

Creative, choreographed, clever.

"Get your Sepsy on"

Thursday, October 1, 2015

Soil Transmitted Helminths in Honduras- Internal Medicine Grand Rounds: Dr. Ana Sanchez

Today we had the honor of hosting Ana Sanchez, PhD at VCU's Medical Grand Rounds.

Dr. Ana Sanchez was invited on the Behalf of the VCU GlobalHealth and Health Disparities Program (GH2DP) - Honduras Program. Dr. Sanchez has collaborated with VCU GH2DP on reducing the burden of soil transmitted helminths in rural Honduran populations. The lecture also covered the immunologic and health impact of helminthic infections in resource poor settings.

We were honored to have her visit VCU and to share both her research and our collaborative experience in a Medical Grand Rounds format.

Phenomenal lecture, excellent turnout.

With Drs. Sanchez and Stevens

Monday, September 28, 2015

The Human Microbial Cloud- Infection Prevention Issue?

This intriguing article was recently forwarded to me.

It is generally accepted that the dissemination of microbes between humans and the inanimate environment can occur through direct contact with surfaces or through airborne release. This last mechanism is very poorly understood. 

The investigative team used 16S rRNA gene sequencing to characterize the airborne bacterial contribution of a single persons sitting in a sanitized custom experimental climate chamber. This was compared to air sampled in an adjacent, identical, unoccupied chamber (control room) as well as supply and exhaust air sources. 

Next, and this is where things really get clever, the microbial burden in settled particles surrounding each occupant was assessed and characterized. 

The results suggests that we shed particles and bacteria in our own distinct and unique way, almost like a bacterial fingerprint. Basically, an occupied space is different microbiologically from an unoccupied space and each participant had their own, distinct microbial cloud.

To me this underscores the dynamic yet still poorly understood mechanism in which we interact with the inanimate environment. Although the bacteria isolated were largely not pathogenic, we certainly cannot exclude that patients colonized or infected with a pathogen will not emit their own 'pathogenic' microbial cloud. The extent to which microbial clouds drive hospital acquired infections is largely unknown.

Until we know better, it may still come down to acknowledging that the inanimate environment is a potential reservoir of hospital pathogens and to employing common sense infection prevention mechanisms to minimize bioburden, such as washing our hands, chlorhexidine bathing patients and performing robust daily and terminal disinfection of hospital rooms.

Friday, September 25, 2015

UCI World Road Championships in Richmond, VA: At VCU Health

It is not often that the UCI Road World Championships are in the USA, let alone 50 feet in front of the VCU Health Infectious Diseases Clinic.

Below are a couple of snaps from yearly today.


View from exam room- VCU ID Clinic, Broad Street, Richmond, VA
Lead riders turning the corner at Governor's Hill and Broad Street, Richmond, VA

Sprint to the finish line- Broad Street,  Richmond, VA

Front of the peloton,  Broad Street, Richmond, VA
The peloton arrives, Broad Street, Richmond, VA

Tuesday, September 22, 2015

Chlorhexidine Impregnated Dressings for Central Venous Catheters- Infection Prevention Benefit

Well, this one seems like old news. Regardless, it was nice to see this review published by the Cochrane Database. The citation is found here.

For the remaining laggards and naysayers, the data resoundingly supports the use of chlorhexidine impregnated dressings over central lines to prevent central line associated bloodstream infections.

Sadly, even with this data, medication impregnated dressings for central lines are not always the standard of care, particularly after patients are discharged on home IV therapy or to long term care / transitional care centers. I routinely see non-impregnated dressings on central lines at the time of outpatient follow up.

The message is clear. Request medication impregnated dressings for central lines and be vigilant and vocal for their continued use in patients with central venous catheters, particularly after hospital discharge.

Thursday, September 17, 2015

Acute HIV Infection- Clinical Symptoms Are Not Reliable

If clinicians feel that they can rely on typical symptoms of acute HIV infection to trigger an HIV PCR test for diagnosis, think again.

Here is a intriguing read published in Clinical Infectious Diseases this month. The investigators review 290 patients (271 males) with primary HIV infection- seroconversion. The majority (70%) had typical symptoms of acute HIV infection, including fever. A significant chunk, 30%, manifested no fever and had atypical presentations, including non-specific neurologic ( encephalitis, prolonged vertigo, paresthesias) and gastrointestinal symptoms (diarrhea, tonsillitis, severe gastritis).  In the study cohort, only in 112 (38%) patients was HIV infection suspected during the first medical attendance. Opportunities to diagnose HIV were missed

The utility of a clinical evaluation to rule out acute HIV infection is limited. 

To me, the message is clear: have a low threshold to test for HIV.

Monday, September 14, 2015

The Richard P. Wenzel Academic Infectious Diseases Consult Service at VCU Medial Center

The ID service at VCU Medical Center has grown by leaps and bounds. 

We now have two general infectious diseases consult services, along with Orthopedic ID and Transplant ID.

Today we officially launched the The Richard P. Wenzel Academic Infectious Diseases Consult Service,  our primary general ID Consult Service, in honor of one of the profession's greatest, modern day infectious diseases specialist.

For more on Dr. Wenzel, click here.

More pictures from the event will be forthcoming.

Congratulations Dr. Wenzel!