I quickly perused this paper with my morning coffee.
Bundled infection prevention practices, particularly for the control of multidrug resistant organisms (MDROs), remain common interventions. The authors performed a scholarly and comprehensive review of the literature.
The conclusion: The review demonstrated that the evidence of the relationship between MDRO infection prevention and control programs and the rates of MDRO infections is weak. There are significant methodologic weaknesses in the MDRO control literature. It is unclear which bundles of interventions are effective. The review suggests, however, that multiple, simultaneous interventions can be effective in reducing MDRO infections.
Here is my take on things: Although we have made much progress in infection prevention, the current state of science and practice is still not sophisticated enough to avert all hospital acquired infections.
Have a fine weekend.