![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7-k704pXXcMlp1u5W6Mvvog1nTiBl-auoHfb9sW4Cdvyd1eFJeQDBeC6i99vpYAiVgOQx0wuWyGiwXjgZSRFGfPORTZmmY_Q8BvM1j4ntRXCWmcKHmMUQkHGy9dZ_y09EnudfVhxllpln/s280/WenzelMicrobiome.png)
We traditionally focus on infection prevention from exogenous threats, with an emphasis on minimizing cross transmission. The majority of surgical site infections, and other healthcare associated infections, come from our own endogenous microbiome.
To more aggressively prevent surgical site infections, in addition to proper surgical hand antisepsis, perioperative antibiotics, perioperative glucose control and perioperative normothermia, our optics should now be on maximal control of the patient's microbiome.
Areas to further explore include improved patient skin antisepsis, to include both the epidermis and dermis, along with better nasal microbiome control via standardized postoperative nasal anti-septic protocols.
Bold infection prevention strategies and paradigm shifts are required for impactful change in outcomes.